The Ocular Cell and Gene Therapy group (OCGT), in the Centre for Gene Therapy and Regenerative Medicine (CGTRM), develops a wide variety of novel cell and gene therapies for the treatment of neurodegenerative diseases, with a particular emphasis on retinal disease.

This is an exciting opportunity to work at the interface of basic and clinical research in a group that is at the forefront of developing novel therapies for retinal disorders, with a major emphasis on translating research into clinical application. Led by Professors Robin Ali and Rachael Pearson (previously at UCL’s Institute of Ophthalmology), it is one of the largest cellular therapy groups in the country and is currently expanding. Over the past 20 years, the group has been optimising cell transplantation to the eye to develop novel therapeutic approaches for eye disease and in particular for disorders affecting the retina, including inherited retinal degeneration. The programme has already led to first-in-human clinical trials of gene and cell therapy for eye disease and we are now in the pre-clinical development phase for clinical trials for photoreceptor cell therapy.