Job Summary

We are seeking applications for a Research Assistant position in the Centre for Haematology, Department of Immunology and Inflammation at Imperial College London, supervised by Dr Deena Iskander.

You will be working alongside Dr Iskander and Professor Anastasios Karadimitris on a project to investigate the role of immune cells and inflammation in Diamond-Blackfan anaemia (DBA), a rare inherited bone marrow failure syndrome. You will explore the impact of inflammation on anaemia and blood cancer (acute myeloid leukaemia) in DBA. This will involve the culturing of primary human cells, and use of high-throughput sequencing techniques to analyse of samples taken from patients with DBA and healthy children.

Duties and responsibilities

  • You will use flow cytometry to isolate CD34+ stem/progenitor cells and mature immune cells from patient samples and process them for cell culture and molecular biology techniques. This will involve the use of high-throughput sequencing techniques, including RNA-seq and related methodologies.
  • As part of your development, you will attend relevant workshops, local research seminars and lab meetings, and will develop contacts within the College and the wider community.

Essential requirements

  • You should have a MSc/MRes in Cell/Molecular Biology or related discipline¬†
  • Have experience working in a research laboratory, and have skills with cell culture, flow cytometry and/or molecular biology work.
  • Experience in the field of haematology is desired, but if you do not have this, training will be provided.