08:30

Registration

09:00

Opening remarks: Launching the London Stem Cell Network

  • Dr. William Grey, John Goodman Fellow, Francis Crick Institute

Tissue/Adult stem cells

Chairs: Dominique Bonnet (The Francis Crick Institute) and Ines Sequeira (King’s College London)
09:05

Key note: Homeostasis in Adult Mammalian Epidermis

  • Fiona Watt, King’s College London
09:40

Postnatal Cell Dynamics; Finding the path towards Oesophageal Homeostasis

  • Jamie McGinn, University of Cambridge
09:55

Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells

  • Joana Carrelha, University of Oxford
10:10

Microenvironmental control of somatic cell plasticity in tissue regeneration

  • Simona Parrinello, University College London
10:35

Coffee break

Cancer Stem Cells

Chairs: Cristina Lo Celso (Imperial College London) and Virginia Turati (University College London)
10:50

In vivo small molecule screens identify TLR7 agonists as potential therapeutics targeting HSPC in MDS5q

  • Beth Payne, University College London
11:15

H3.3-K27M Expression and Trp53 Loss in Embryonic Neural Stem Cells Induces Gliomagenesis

  • Manav Pathania, University College London
11:30

Integrative profiling, xenograft and genomics reveal JMML’s origin

  • Kevin Rouault-Pierre, Barts Cancer Institute
11:30

A human IPS model implicates embryonic B-myeloid fate restriction as a developmental susceptibility to ETV6-RUNX1

  • Simon Richardson, University College London
12:00

Tracing stem cell architecture in vivo in human tissues and cancer

  • Trevor Graham, Queen Mary, University of London
12:35

Lunch and Posters

Bioengineering the stem cell environment

Chairs: Davide Danovi (King’s College London) and Diana Passaro (The Francis Crick Institute)
13:45

Stem cell-derived organoids: disease modelling and regenerative medicine

  • Vivian Li, The Francis Crick Institute
14:10

Vascularisation for whole organ tissue engineering

  • Alessandro Filippo Pellegata, University College London
14:25

In-Silico control of Wnt/β-catenin pathway in mammalian cells using microfluidics

  • Elisa Pedone, University of Bristol
14:50

Unravelling how bi-directional cell-biomaterial interactions direct stem cell fate in 3D

  • Eileen Gentleman, King’s College London

Regenerative medicine

Chairs: Molly Stevens (Imperial College London) and Luca Pinton (University College London)
15:15

Mechanisms of lineage specification in human embryos

  • Kathy Niakan, The Francis Crick Institute
15:40

Dickkopf-3 binds to CXCR7 inducing vascular progenitor cell migration and degradable graft cellularisation

  • Shirin Issa Bhaloo, King’s College London
15:55

Potential of patient-derived ear and fat stem cells for the reconstruction of congenitally malformed ear cartilage

  • Eleonora Zucchelli, University College London
16:10

Cell and Gene Therapy for Lung Cancer

  • Samuel Janes, University College London
16:35

Coffee break

Concluding remarks

Chair: Sian Harding (Imperial College London)
16:55

Therapeutic Angiogenesis in Ischemic Disease: Cellular and Acellular Options

  • Costanza Emanueli, Imperial College and University of Bristol
17:35

Awards

17:40

Closing remarks

Ines Sequeira, King’s College London
17:50

Posters, Drinks and Networking