Programme

Morning session

09:00

Registration opens

Tea, coffee, pastries
09:30

Opening remarks

  • Dr. Rob Hynds, Group Leader, GOS Institute of Child Health, University College London
10:30

Dissecting the cross-talk between normal, leukaemia stem cells and the bone marrow microenvironment

  • Prof. Dominique Bonnet, Group Leader, Francis Crick Institute

Disease Modelling (Chair: Inês Sequeira, Queen Mary’s University London)

10:30

Mutant clones in normal epithelium outcompete and eliminate emerging tumors

  • Bartomeu Colom, Sanger Institute
10:25

A Complex Interplay of Intra- and Extracellular Factors Regulates the Outcome of Foetal- and Adult-Derived MLL-Rearranged Leukaemia

  • Maria Jassinskaja, Lund University and The University of York
10:40

Mapping Waddington’s Landscape: Towards a Theory of Cell Fate Decisions

  • James Briscoe, The Francis Crick Institute
11:05

Flash Poster Presentations

  • Laura Mincarelli, Earlham Insitute
  • Esther Palomino Lago, Royal Veterinary College
11:15

Coffee Break and Poster Viewing

Translational Medicine (Chair: Sara Rankin, Imperial College London)

11:35

Using iPSC to develop precision medicines for childhood movement disorders

  • Manju Kurian, UCL Great Ormond Street Institute of Child Health
12:00

Persistent Hif1a-Sox9 activation poses barriers to epithelial cell plasticity during oesophagealto-skin lineage conversion

  • Paula Jimenez Gomez, University of Cambridge
12:15

Stromal contribution to pre-neoplastic lesion formation

  • Greta Skrupskelyte, University of Cambridge
12:30

Flash Poster Presentations

  • Peter Harley, King’s College London
  • Leong Yeh Chwan, University College London
12:40

Lunch Break

13:00

‘Guess the Organoid’ Quiz

By STEMCELL Technologies
13:20

Industry Careers Session sponsored by bit.bio, BioTechne, Jellagen, ProteinTech, Qkine

  • Katia Nazmutdinova, Encelo
  • Davide Danovi, bit.bio
  • Andre da Costa, AstraZeneca

Pluripotency and Development (Chair: Gabor Foldes, Imperial College London)

14:00

Leveraging CRISPRi screens in tissue-derived organoids to study human lung development

  • Dawei Sun, University of Cambridge
14:15

hPSC Research: The Right Tools for Each Project

  • Camille Lemey, STEMCELL Technologies
14:30

USP7 facilitates endocrine differentiation in the pancreas by stabilising NGN3

  • Teodora Manea, Kings College London
14:45

Role of the Haematopoietic Stem Cell Niche in Re-establishing Homeostasis Upon Stress

  • Tiago Luis, Imperial College London
15:10

Flash Poster Presentations

  • Tommy Mau, Imperial College London
  • Ioakeim Ampartzidis, University College London
15:20

Coffee Break and Poster Viewing

Post-natal Stem Cells (Chair: William Grey and Rob Hynds)

15:50

Neural stem cells alter nucleocytoplasmic partitioning and accumulate nuclear polyadenylated transcripts during quiescence

  • Rita Sousa-Nunes, Kings College London
16:15

Identification and characterisation of epithelial stem cells in the human postnatal thymus

  • Roberta Ragazzini, The Francis Crick Institute
16:30

Keynote Lecture: Organoids to Model Human Diseases

  • Hans Clevers, The Hubrecht Institute, The Netherlands
17:15

Closing Remarks & Awards

  • William Grey, LSCN Committee
17:20

Drinks reception

With live music from the Crick Orchestra